Ademetionine 1,4-Butanedisulfonate

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Sell Ademetionine 1,4-Butanedisulfonate Ademetionine 1,4-Butanedisulfonate
HANGZHOU HUAJIN PHARMA CO.,LTD.

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Ademetionine 1,4-Butanedisulfonate

This medicine is the new medicine, there is very few family factory production on international . It Is suitable for  the result of in the liver in front of liver cirrhosis and liver cirrhosis the bile to be pent-up; In the gestation period liver the bile is pent-up.
The gland glucoside methionine is exists in human body all organizations and the body fluid one biological activity member. It (transfers methyl function) as the methyl donor and the physiology  base compound (for example cysteine, taurine, Guguangantai and coenzyme A and so on) the precursor (transfers sulfenyl function) to participate in vivo important biochemistry response. In the liver, through causes the protoplasmic membrane phosphatide methylation but to adjust the liver cell membrane the fluidity, moreover through transfers the sulfenyl to respond may promote in the disintoxicating process the curing product synthesis. So long as in the liver the gland glucoside methionine biological exploitability in the normal range, these responses is helpful in prevented in the liver the bile is pent-up.
Already discovered, when liver cirrhosis the liver gland glucoside methionine synthesis obviously drops, this was because the gland glucoside methionine synthesis enzyme (catalyzed essential amino acids methionine transforms to gland glucoside methionine) the active remarkable drop (-50%) is the result of. This kind of metabolism barrier causes the methionine to reduce to the gland glucoside methionine transformation, thus weakened had prevented the bile was pent-up normal physiological process. The result causes in liver cirrhosis patient diet the methionine blood plasma percentage clearance to reduce, and creates its metabolite, specially cysteine, Guguangantai and taurine exploitability drop. Moreover this kind of metabolism barrier also creates the high methionine blood sickness, causes to have the liver brain illness risk increase. Some research proved in vivo methionine accumulates may cause its degradation product (for example mercaptane, methanthiol) to elevate in the blood density, but these degradation products at in liver brain illness pathogenesis vital role. Because the gland glucoside methionine by makes  the base compound synthesis to increase, but does not increase in the blood circulation the methionine density, for liver cirrhosis patient supplemented the gland glucoside methionine may cause one kind when the disease of the liver the biological exploitability reduces the essential compound restores its level.





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Category : Pharmaceutical Raw Materials
Country Of Origin : China
Listing Type : Sell
Contact : shen weihua
Address : NO.18, Tangmiao Road
Xihu District
Hangzhou, Zhejiang, 310013
China
Telephone : [86] (571) 28950030
Fax : [86] (571) 85126395



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