You May Also Be Interested In:
The 5-Fluoroorotic Acid purity is >98% or > 99% (by HPLC) . ; Molecular Formula: C5H3FN2O4; CAS number: 703-95-7.
Properties: 5-Fluoroorotic Acid (5-fluorouracil-6-carboxylic acid monohydrate; 5-FOA) is widely used in yeast molecular genetics. 5-FOA is toxic to yeast cells with a functioning URA3 gene encoding orotidine5'-monophosphate decarboxylase (OMP decarboxylase) . 5-FOA is therefore especially useful for the selection and identification of mutant yeast strains. 5'-FOA's use in the yeast 2-hybrid system allows the construction of activation domain hybrid libraries to identify protein-protein interactions (1)