Artichoke leaf extract(chlorogenic acid) 3%
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artichoke leaf extract
Artichoke leaf extract is widely used alone or in association with other herbs for embittering alcoholic and soft drinks and to prepare herbal teas or herbal medicinal products.
Artichoke leaf extract has been tested in heartburn, also known as dyspepsia. It has also been tested in irritable bowel syndrome and high cholesterol.
Artichoke leaf extract for treating hypercholesterolaemia.
BACKGROUND: Hypercholesterolaemia is directly associated with an increased risk for coronary heart disease and other sequelae of atherosclerosis. Artichoke leaf extract (Artichoke leaf extract) , which is available as an over-the-counter remedy, has been implicated in lowering cholesterol levels. Whether Artichoke leaf extract is truly efficacious for this indication, however, is still a matter of debate. OBJECTIVES: To assess the evidence of Artichoke leaf extract versus placebo or reference medication for treating hypercholesterolaemia defined as mean total cholesterol levels of at least 5.17 mmol/L (200 mg /dL) . REVIEWER'S CONCLUSIONS: Few data from rigorous clinical trials assessing Artichoke leaf extract for treating hypercholesterolaemia exist. Beneficial effects are reported, the evidence however is not compelling. The limited data on safety suggest only mild, transient and infrequent adverse events with the short term use of Artichoke leaf extract. More rigorous clinical trials assessing larger patient samples over longer intervention periods are needed to establish whether Artichoke leaf extract is an effective and safe treatment option for patients with hypercholesterolaemia.