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Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection.Entecavir is a nucleoside analog[1] (more specifically, a guanine analogue) that inhibits reverse transcription, DNA replication and transcription in the viral replication process.Entecavir is used to treat chronic hepatitis B. It also helps prevent the hepatitis B virus from multiplying and infecting new liver cells. Entecavir is also indicated for the treatment of chronic hepatitis B in adults with HIV/AIDS infection
The clinical efficacy of entecavir has been studied in several randomized, doulbe-blind, multicentre trials. Oral entecavir was an effective and generally well tolerated treatment