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Chemtrue. One-Step H. Pylori Antigen Test is a rapid, visual immunochromatographic test for the qualitative detection of Helicobacter Pylori antigen in fecal samples. This test is intended as an aid in the diagnosis of Helicobacter Pylori infection. The test is recommended for professional use. Helicobater pylori are gram negative bacteria that infect gastric mucosa. Infection with Helicobacter pylori may lead to chronic gastritis and predispose to gastric and duodenal ulcers. Infection with H. pylori is very common and has been estimated to occur in 40-50% of the population in developed countries and 80-90% of the population in developing regions.