Herbs and herbal products
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We Packiam Botanicals offer Gymnema sylvestre leaves.
Gymnema Sylvestre reduces blood sugar level
Gymnema Sylvestre, also known as Gurmar and Meshashringi, whose Hindi name literally means 'sugar destroyer', has been used in Ayurveda for several centuries to regulate sugar metabolism. Gymnema has been used in India for the treatment of diabetes for over 2,000 years.
The hypoglycemic (blood sugar-lowering) action of gymnema leaves was first documented in the late 1920s. This action is gradual in nature, differing from the rapid effect of many prescription hypoglycemic drugs. Gymnema leaves raise insulin levels by regeneration of the cells in the pancreas that secrete insulin. Other research has shown that gymnema also improves uptake of glucose into cells by increasing the activity of the glucose utilizing enzymes, and prevents adrenaline from stimulating the liver to produce glucose, thereby reducing blood sugar levels. The leaves are also noted for lowering serum cholesterol and triglycerides. It also abolishes the taste of sugar, which effectively suppresses and neutralizes the craving for sweets.
The primary clinical application for this botanical is as an antidiabetic agent. Gymnema has been the subject of considerable research since the 1930s, with promising results for types 1 and 2 diabetes. Gymnema has been successful in controlling the blood sugar level without reducing it to below the normal blood sugar level, an effect seen with the use of insulin or oral hypoglycemic sulphonylurea compounds. Gymnema provides a simple and effective method to help maintain healthy glucose levels. Gymnema contains Gymnemic acid (GA) , quercitol, lupeol, _-amyrin and stigmasterol, which have glucose lowering properties. It works safely within your current regimen to promote proper pancreatic function.
Historical or traditional use (may or may not be supported by scientific studies) : The leaves were also used for stomach ailments, constipation, water retention, and liver disease.
The leaves are also noted for lowering serum cholesterol and triglycerides.5 While studies have shown that a water-soluble acidic fraction of the leaves provides hypoglycemic actions, the specific constituent responsible for this action has not been clearly identified. Some researchers have suggested gymnemic acid as one possible candidate.6 However, further research is needed to clearly determine which constituent is responsible for this effect. Gurmarin, another constituent of the leaves, and gymnemic acid have been shown to block the ability in humans to taste sweets.7
How much is usually taken? Double-blind clinical trials in India have used 400 mg per day of a water-soluble acidic fraction of the gymnema leaves. In type 2 diabetics, ongoing use for periods as long as 18 to 24 months has proven successful.8 In type 1 (insulin-dependent) diabetes patients, a similar amount has been used successfully as an adjunct to ongoing use of insulin.9 The extract used in these trials contains approximately 2,990 gymnemic acids. Consult closely with a physician, as insulin amounts may need to be lowered while taking gymnema. Traditionally, 24 grams per day of the leaf powder is used.
Are there any side effects or interactions? Used at the amounts suggested, gymnema is generally safe and devoid of side effects. The safety of gymnema during pregnancy and breast-feeding has not yet been determined. People with diabetes should only use gymnema to lower blood sugar under the clinical supervision of a healthcare professional. Gymnema cannot be used in place of insulin to control blood sugar by people with either type 1 or type 2 diabetes.