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Hyaluronic acid (abbreviated as HA, also called sodium hyaluronate) is a straight chain macromolecular mucopolysaccharide composed of repeat disaccharide units of glucuronicacid and N-acetylglucosamine, which exists in the connective tissues of human and animals, including extra cellular space of human and animal tissues, vitreums, umbilical cords, skin joints synovia and cockscomb. Its molecular weight ranges from several ten thousand to several million. Its solution has extraordinary quality of keeping moisture, high viscoelasticity and lubricity. The applications are cosmetics, pharmacy and health and beauty food.