Sell Mycophenolate Mofetil

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We offer a very competitive price for MMF and MMP and are interested in opening up new markets. We have just increased production so we are looking for more distribution channels and end users. Please contact Shanghai Trifecta Pharma for more information.


MYCOPHENOLATE MOFETIL
PRODUCT IDENTIFICATION

CAS NO. 128794-94-5


FORMULA C23H31NO7
MOL WT. 433.49
H. S. CODE

TOXICITY

DERIVATION

SYNONYMS Mycophenolic acid 2-morpholinoethyl ester;
4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5- isobenzofuranyl) -4- methyl-, 2-(4-morpholinyl) ethyl ester; 2-Morpholinoethyl (E) -6-(l,3-dihydro-4-hydroxy-6- methoxy-7- methyl-3- oxo-5-isobenzofuranyl) -4- methyl-4-hexenoate
CLASSIFICATION

PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL STATE White to off-white crystalline powder
MELTING POINT
BOILING POINT
SPECIFIC GRAVITY
SOLUBILITY IN WATER
pH
VAPOR DENSITY

AUTOIGNITION


NFPA RATINGS

REFRACTIVE INDEX

FLASH POINT

STABILITY Stable under ordinary conditions.
APPLICATIONS

Mycophenolate, 2-morpholinoethyl ester of mycophenolic acid, is a guanine monophosphate synthesis inhibitor by interfering with the synthesis of inosine mononophosphate dehydrogenase (IMPDH) , resulting in inhibiting the proliferation of cells, especially leukocytes and lymphocytes. It is more lymphocyte-specific than azathioprine. Mycophenolate is an immunosuppressive agent used in conjunction with cyclosporine and corticosteroids to prevent rejection of allogeneic renal transplants. Mycophenolate mofetil is a white to off-white crystalline powder; soluble in acetone and methanol, and sparingly soluble in water and ethanol; administered orally. The chemical designation is 2-morpholinoethyl (E) -6-(l,3-dihydro-4-hydroxy-6-methoxy-7- methyl-3-oxo-5-isobenzofuranyl) -4- methyl-4-hexenoate.
SALES SPECIFICATION
APPEARANCE
White to off-white crystalline powder
IDENTIFICATION
Complies

ASSAY (HPLC)
97.5 - 100.5%
LOSS ON DRYING
2.0% max

HEAVY METALS 20ppm max

RELATED SUBSTANCES 1.0% max (FREE ACID: 0.5 max)
TRANSPORTATION
PACKING

HAZARD CLASS
UN NO.
GENERAL DESCRIPTION OF IMMUNOSUPPRESSIVE DRUGS
Immunosuppressants are drugs to prevent transplant rejection after organ transplantation by inhibiting the reaction of the immune system and suppression of body's ability to recognize and destroy foreign substances. But they also reduce the ability of the immune system to fight infections, resulting in vulnerable body to opportunistic infections and risk of developing certain cancers. Most of immunosuppressants suppress the whole immune system. Globulin types used in combination with other immunosuppressants and monoclonal antibodies suppress specific parts of the immune system. Immunosuppressions are also used to counteract autoimmune diseases characterized by an overactive immune response, whereby the body own immune defense mechanisms are inappropriately directed against the normal tissue that lines the joints and connective tissue in many other parts of the body, such as the blood vessels and lungs, resulting in organ damage or activation of a systemic immune response. Immunosuppressive drugs can be classified into groups as follows:
Corticosteroids
Dexamethasone
Prednisolone
Prednisone
Polyclonal antibodies
Antilymphocyte globulin
Antithymocyte globulin
Macrolides
Sirolimus
Tacrolimus
Antimetabolites
Azathioprine
Cyclophosphamide
Methotrexate
Monoclonal antibodies
Basiliximab
Daclizumab
Infliximab
Muromonab
Fungal metabolite
Cyclosporine
Others
Glatiramer acetate
Mycophenolate mofetil
Interferons
Opioids
Tumor necrosis factor (TNF) inhibitors