Sell NICLOSAMIDE

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SPECIFICATION OF NICLOSAMIDE

SR. NO. TEST SPECIFICATION
1 Description Yellowish white or Yellowish, fine crystals Powder.
2 Solubility Sparingly soluble in Acetone, Slightly soluble in Ethanol, Practically insoluble in water.
3 Identification 1. Melting point: 2270C to 2320C2. Examine by infrared absorption spectrophotometry(2.2.24) , comparing with the spectrum obtained with anhydrous niclosamide CRS. Examine as disc prepared using about 0.5 mg of substance and 0.3 g of potassium bromide R.
4 Loss on Drying Not More than 0.5 % w/w
5 Melting Range 2270 C to 2320 C
6 Sulphated Ash Not More than 0.1 % w/w
7 Related substances Not More Thane 0.2%
8 Chloride content Not More Thane 500 ppm
9 5- Chlorosalicylic Acid Not More Thane 60 ppm
10 2- Chloro 4-nitroaniline Not more Thane 100 ppm
11 Assay 98% to 101%Calculated on Dried Basis.