Passion Flower Extract
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passion flower extract
Product Name: Passion Flower Extract, Flavonoids.2%4%CAS. NO.008057-62-3. Passiflora incarnata extract, Passiflora extract, Passionflower extract. Serie No: S-051
Place of Origin: China Brand Name: MDidea Extracts Professional
Quality/Safety Certifications:GMP Price Terms:EXW, CNF, CIF.
Minimum Order:1~25kilos Payment Terms:Transfer.
Delivery Lead Time:1~3 days Supply Ability:500kilos+
Passion Flower Extract, Flavonoids.2%4%CAS. NO.008057-62-3. Passiflora incarnata extract, Passiflora extract, Passionflower extract.
Scientific names: Passiflora incarnata, occasionally P. lutea.
Common names: Passion flower also is known as passion fruit, granadilla (species with edible fruit) ; water lemon; Maypop, apricot vine, wild passion flower (P. incarnatus) ; and Jamaican honeysuckle (P. laurifolia) .
Botanical Source:Passiflora spp. flower petals of Passiflora spp, Passion Flower Extract, Flavonoids.
Common Names&Synonyms:Passion Vine; Maracuja; Apricot Vine; Maypop, Maracuja, passionflower, carkifelek, charkhi felek, maypop, maypop
passionflower, saa't gulu, ward assa'ah, apricot vine, maypop herb, purple passion flower, passion vine, zahril aalaam, granadilla, passionvine, maracoc, apricot
-vine, saa't gulu, ward assa'ah, zahril aalaam
Phytochemicals and Constituents:
Constituents: Alkaloids; harmine, harman, harmol, harmaline, harmalol, and Passiflorin.
Flavonoids: apigenin and various glycosides, homoorientin, isovitexin, kaempferol, luteolin, orientin, quercitin, rutin, saponaretin, saponarin and vitexen.
Chemical Composition:Alkaloids, Apigenin, Carbohydrates, Coumarins, Flavonoids, Fructose, Glucose, Gum,
Harmaline, Harmalol, Harman, Harmine, Maltol, Plant alcohols, Orientin, Raffinose,
Saponaretin, Saponarin, Scopoletin, Stigmasterol, Sitosterol, Sterols, Sucrose, Umbelliferone, Vitexin.
Chemical analysis on passionflower indicates it contains three main groups of active chemicals: alkaloids, glycosides and flavonoids. Interestingly, when the glycosides and flavonoids are isolated and tested individually they have demonstrated the opposite effects for which the plant is commonly used for. Only when the two groups of chemicals are combined as a whole herb, do researchers observe the plant's sedative effect. Passionflower also contains naturally occurring serotonin as well as a chemical called maltol which has documented sedative effects (and which might explain the natural calming properties of passionflower) . A group of harmane alkaloids in passionflower have demonstrated antispasmodic activity and the ability to lower blood pressure. In addition, a flavonoid named chrysin has demonstrated significant antianxiety activity.
The main plant chemicals in passionflower include: alkaloids, alpha-alanine, apigenin, aribine, chrysin, citric acid, coumarin, cyclopassifloic acids A-D, cyclopassiflosides I-VI, diethyl malonate, edulan I, edulan II, flavonoids, glutamine, gynocardin, harmane, harmaline, harmalol, harmine, harmol, homoorientin, isoorientin, isoschaftoside, isovitexin, kaempferol, loturine, lucenin-2, lutenin-2, luteolin, n-nonacosane, orientin, passicol, passiflorine, passifloric acid, pectin, phenolic acids, phenylalanine, proline, prunasin, quercetin, raffinose, sambunigrin, saponarin, saponaretin, saponarine, schaftoside, scopoletin, serotonin, sitosterol, and stigmasterol.
There is some controversy over the exact composition of P. incarnata. Approximately 2.5 percent appears to be flavonoids such as vitexin, orientin, homo-orientin, saponarin, schaftoside, and a few others as glucosides, together with free flavonoids including apigenin, luteolin, quercetin, and kaempferol.
In Europe, passionflower is required to contain not less than 0.8 percent total flavonoids, calculated as vitexin.
The harman alkaloids that have been identified by some chemists are disputed by others. Umbelliferone, scopoletin, and maltol have been reported.
An antifungal, antimicrobial compound dubbed passicol is found in fresh plant matter but dissipates quickly from the dried herb or aqueous extract.
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for mood disorders (depression, anxiety, stress)
for insomnia and sleep disorders
for headaches, migraines and general pain
for stomach problems (colic, nervous stomach, indigestion, etc. )
to relieve menstrual cramps and premenstrual syndrome (PMS)
Properties/Actions Documented by Research:
analgesic (pain-reliever) , anti-anxiety, anti-inflammatory, antispasmodic, cough suppressant, aphrodisiac, cough suppressant, central nervous system depressant, diuretic, hypotensive (lowers blood pressure) , sedative
Other Properties/Actions Documented by Traditional Use:
anticonvulsant, antidepressant, astringent, cardiotonic (tones, balances, strengthens the heart) , disinfectant, nervine (balances/calms nerves) , neurasthenic (reduces nerve pain) , tranquilizer, vermifuge (expels worms)
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Passion Flower Extract. Flavonoids 2%,4%HPLC
Description: Passion Flower Extract.
Plant Part Used: Aerial Part of Passiflora spp.
Content Standardized: Flavonoids 2%,4%HPLC
Serie Code: S-051
Expiration Date: 18~24Months in Good Condition
Storage Stock: Bulk in Stock
Pricing Terms: C&F; CIF; DDU; DDP.
Delivery Arrange: Soonest on the Day Confirmed
Appearance Showing: Light Yellow Brown Fine Powder
Extracts State: Fine Crystal Powder
Mesh Size: 100% Pass 80 Mesh Screen
Color: Light Yellow Brown
Odor and Smell: Charateristics Aromatic
Taste Sense: Characteristics.
Bulk Density: 0.47~0.49g/ml.
Preparations & Dosage:
Infusion: pour a cup of boiling water onto lteaspoonful of the dried herb and let infuse for l5 minutes. Drink a cup in theevening for sleeplessness, and a cup twice a day for the easing of otherconditions. Tincture: take l-4 ml of the tincture and use the same way as theinfusion.
Dosing: Dosages---3 to 10 grains. Of Fluid extract, 10 to 20 minims.
The below doses are based on scientific research, publications, traditional use, or expert opinion. Many herbs and supplements have not been thoroughly tested, and safety and effectiveness may not be proven. Brands may be made differently, with variable ingredients, even within the same brand. The below doses may not apply to all products. You should read product labels, and discuss doses with a qualified healthcare provider before starting therapy.
Standardization: Standardization involves measuring the amount of certain chemicals in products to try to make different preparations similar to each other. It is not always known if the chemicals being measured are the "active" ingredients. While there is no widely accepted standardization for passion flower, the flavonoid components have been used for standardization in some commercial products.
Adults (18 years and older) :
General: Safety and effectiveness have not been established for any dose. There are no standard or well-studied doses of passion flower. Different preparations and doses have been used traditionally.
Dried herb: 0.5 to 2 grams taken 3 to 4 times daily by mouth has been used.
Tincture(1:8) : 1 to 4 milliliters taken 3 to 4 times daily by mouth has been used.
Tea: Tea made from 4 to 8 grams of dried herb, taken daily has been used.
Infusion: 2.5 grams has been used 3 to 4 times daily.
Children (younger than 18 years) :
There is not enough scientific data to recommend passion flower for use in children at any dose.
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What is Passion Flower?
The term !0passion flower!1 connotes many of the approximately 400 species of the genus Passiflora, which primarily are vines. Some of the species are noted for their showy flowers, others for their edible fruit. Common species include P. incarnata, P. edulis, P. alata, P. laurifolia, and P. quadrangularis. Those with edible fruit include P. incarnata, P. edulis, and P. quadrangularis, the last being one of the major species grown for its fruit. Passiflora species are native to tropical and subtropical areas of the Americas. In the US, P. incarnata is found from Virginia to Florida and as far west as Missouri and Texas. The flowers of Passiflora have 5 petals, sepals, and stamens, 3 stigmas, and a crown of filaments. The fruit is egg-shaped, has a pulpy consistency, and includes many small seeds.
What is Passion Flower used for?
The passion flower was discovered in 1569 by Spanish explorers in Peru who saw the flowers as symbolic of the passion of Christ, and therefore a sign of Christ's approval of their efforts. This is the origin of the scientific and common names. The folklore surrounding this plant possibly dates further into the past. The floral parts are thought to represent the elements of the crucifixion (3 styles represent 3 nails, 5 stamens for the 5 wounds, the ovary looks like a hammer, the corona is the crown of thorns, the petals represent the 10 true apostles, and the white and bluish purple colors are those of purity and heaven) .
Passion flower has been used to treat sleep disorders and historically in homeopathic medicine to treat pain, insomnia related to neurasthenia or hysteria, and nervous exhaustion.
The pharmacological activity of Passiflora is attributed primarily to the alkaloids and falvonoids. The harmala alkaloids inhibit monoamine oxidase, which may account for part of their pharmacologic effects. Harmala alkaloids include harmine, harmaline, and harmalol. Different parts of the plant and different species have varying amounts of the active alkaloids. The official passion flower is considered to be P. incarnate, which is used for the drug.
Passiflora exhibits sedative and anti-anxiety activity in laboratory animals. Human studies of Passiflora, in combination products, have also demonstrated anti-anxiety and sedative properties. One study of short duration showed contradictory results. While early studies show some promise, more studies are needed to prove the tranquilizing and sedative properties of Passiflora in humans.
Passion flower's ability to reduce anxiety makes it potentially useful for asthma, palpitations and other cardiac rhythm abnormalities, high blood pressure, insomnia, neurosis, nervousness, pain relief, and other related conditions. While there are some indications of its effectiveness, little clinical research is available to validate these medical uses. Other uses of passion flower include herbal treatment for menopausal complaints, for its antimicrobial activity, and as a flavored syrup to mask drug taste.
What is the dosage of Passion Flower?
No clinical trials of passion flower as a single agent have been reported. Therefore, the daily dose of 4 to 8 g currently is not supported.
Is Passion Flower safe?
Contraindications have not yet been identified.
Documented adverse effects. Avoid use. Passion flower is a known uterine stimulant.
None well documented.
Though no adverse effects of passion flower have been reported, large doses may result in CNS depression.
No major clinical trials have been conducted to assess the plant''''''''s toxicity.