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Propolis is a substance made by the honeybee that provides protection against harmful bacteria, viruses and fungi. Propolis is plant resin collected by bees for use in and around the hive. In plants it is usually the sticky coating around buds that serves to protect them from the elements of weather plus from attack by bacteria, fungi, molds, and viruses. These are properties that are useful to the bees and are enhanced by the sticky properties of the propolis. Like pollen, propolis is a bee product that cannot be clearly defined and varies from sample to sample. This is a natural outcome of the collection process. Propolis collecting bees will use resins from a large variety of tree and other plant species, and these naturally will differ in their qualitative and quantitative chemical composition. Nevertheless, different propolis samples do share considerable similarity in their physical and overall general chemical nature.