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The bark of the West African yohimbe tree is a traditional aphrodisiac and the source of yohimbine, a prescription drug for impotence.
Yohimbine (the drug) is only modestly effective at best, better than placebo but only successful in about 30 to 45% of the men who use it.1 However, it seems to work even in men whose impotence is caused by a serious illness such as diabetes.
One small double-blind study on women found yohimbine combined with arginine to be somewhat effective for treating women with sexual dysfunction.2
An open trial of yohimbine alone to treat sexual dysfunction induced by the antidepressant fluoxetine (Prozac) found improvement in eight out of nine people, two of whom were women.3 However, in the absence of a placebo group, these results can't be taken as reliable; in addition, there are concerns about the safety of combining yohimbe with antidepressants.
Treating impotence, it also has been shown to be effective in treating sexual dysfunction caused by psychological reasons, like stress, tension and fatigue and combating against weight loss.